Para-Cresidine

Para-Cresidine Structure
Para-Cresidine structure
Common Name Para-Cresidine
CAS Number 120-71-8 Molecular Weight 137.179
Density 1.0±0.1 g/cm3 Boiling Point 235.4±20.0 °C at 760 mmHg
Molecular Formula C8H11NO Melting Point 50-52 °C(lit.)
MSDS Chinese USA Flash Point 102.1±15.0 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

Development of QSAR models for predicting hepatocarcinogenic toxicity of chemicals.

Eur. J. Med. Chem. 44 , 3658-64, (2009)

A dataset comprising 55 chemicals with hepatocarcinogenic potency indices was collected from the Carcinogenic Potency Database with the aim of developing QSAR models enabling prediction of the above unwanted property for New Chemical Entities. The dataset was...

Biopartitioning micellar chromatography to predict mutagenicity of aromatic amines.

Eur. J. Med. Chem. 42 , 1396-402, (2007)

Mutagenicity is a toxicity endpoint associated with the chronic exposure to chemicals. Aromatic amines have considerable industrial and environmental importance due to their widespread use in industry and their mutagenic capacity. Biopartitioning micellar chr...

Chromosome 11 allelotypes reflect a mechanism of chemical carcinogenesis in heterozygous p53-deficient mice.

Carcinogenesis 22(1) , 89-98, (2001)

Mice heterozygous for a null p53 allele were administered three well-characterized carcinogens to learn more about mechanisms of carcinogenesis and to evaluate the p53-deficient mouse as a tool for identifying potential human carcinogens. Benzene-induced sarc...

Toxicity and carcinogenicity studies of chlorpromazine hydrochloride and p-cresidine in the p53 heterozygous mouse model.

Toxicol. Pathol. 30(6) , 696-704, (2002)

The carcinogenic potential of chlorpromazine hydrochloride, a psychotropic agent, was assessed in the p53 heterozygous mouse assay. In a 4-week dose range finding study in p53 wild-type mice, doses of 20,40, 60, and 80 mg/kg were poorly tolerated because of m...

Morphology of nasal cavity neoplasms in F344 rats after chronic feeding of p-cresidine, and intermediate of dyes and pigments.

Anticancer Res. 1(5) , 279-86, (1981)

p-Cresidine was administered in the feed at either of two concentrations (0.5 and 1.0 percent) to groups of 50 male and 50 female F344 rats for 104 weeks. Fifty animals of each sex were placed on test as controls and fed only the basic laboratory diet. All an...

Comments on the paper 'The non-genotoxicity to rodents of the potent bladder carcinogens o-anisidine and p-cresidine'.

Mutat. Res. 279(3) , 223-6, (1992)

meta- and para-Cresidine.

IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 27 , 91-101, (1982)

p-Cresidine.

Rep. Carcinog. 12 , 122-3, (2011)

p-Cresidine.

Rep. Carcinog. 11 , III72-3, (2004)

p-Cresidine.

Rep. Carcinog. 10 , 71-2, (2002)