Thalidomide D4 structure
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Common Name | Thalidomide D4 | ||
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CAS Number | 1219177-18-0 | Molecular Weight | 262.25400 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C13H6D4N2O4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Thalidomide D4Thalidomide D4 is a deuterium labeled Thalidomide. Thalidomide is initially promoted as a sedative, inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ~250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties[1][2]. |
Name | 4,5,6,7-tetradeuterio-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione |
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Synonym | More Synonyms |
Description | Thalidomide D4 is a deuterium labeled Thalidomide. Thalidomide is initially promoted as a sedative, inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ~250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties[1][2]. |
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Related Catalog | |
Target |
Kd: ~250 nM (CRL4CRBN)[1] |
References |
Molecular Formula | C13H6D4N2O4 |
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Molecular Weight | 262.25400 |
Exact Mass | 262.08900 |
PSA | 87.04000 |
LogP | 0.30160 |
|A-Phthalimidoglutarimide-d4 |
Myrin-d4 |
3-Phthalimidoglutarimide-d4 |
Celgene-d4 |
Contergan-d4 |
Thalidomide-d4 |
Distaval-d4 |
Kevadon-d4 |