GSK 9027
Modify Date: 2025-10-11 20:22:12
GSK 9027 structure
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Common Name | GSK 9027 | ||
|---|---|---|---|---|
| CAS Number | 1229096-88-1 | Molecular Weight | 525.51700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H19F4N3O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GSK 9027GSK9027, as a non-steroidal glucocorticoid receptor (GR) agonist, behaves as a partial agonist on the 2×glucocorticoid response element (GRE) reporter system, and achieves intrinsic activities relative to dexamethasone[1][2]. |
| Name | gsk9027 |
|---|
| Description | GSK9027, as a non-steroidal glucocorticoid receptor (GR) agonist, behaves as a partial agonist on the 2×glucocorticoid response element (GRE) reporter system, and achieves intrinsic activities relative to dexamethasone[1][2]. |
|---|---|
| Related Catalog | |
| Target |
GR[2] |
| In Vitro | GSK9027 demonstrates reduced 2×GRE reporter activation and is partial agonists[2]. |
| References |
| Molecular Formula | C27H19F4N3O2S |
|---|---|
| Molecular Weight | 525.51700 |
| Exact Mass | 525.11300 |
| PSA | 72.37000 |
| LogP | 7.94610 |
| InChIKey | DXBJGDVBQPEMOB-UHFFFAOYSA-N |
| SMILES | O=S(=O)(Cc1ccccc1)Nc1ccc(-c2ccc3c(cnn3-c3ccc(F)cc3)c2)c(C(F)(F)F)c1 |