GSK 9027

Modify Date: 2024-01-16 07:45:05

GSK 9027 structure	Common Name	GSK 9027
	CAS Number	1229096-88-1	Molecular Weight	525.51700
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₁₉F₄N₃O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GSK 9027

GSK9027, as a non-steroidal glucocorticoid receptor (GR) agonist, behaves as a partial agonist on the 2×glucocorticoid response element (GRE) reporter system, and achieves intrinsic activities relative to dexamethasone[1][2].

Name	gsk9027

Description	GSK9027, as a non-steroidal glucocorticoid receptor (GR) agonist, behaves as a partial agonist on the 2×glucocorticoid response element (GRE) reporter system, and achieves intrinsic activities relative to dexamethasone[1][2].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor
Target	GR[2]
In Vitro	GSK9027 demonstrates reduced 2×GRE reporter activation and is partial agonists[2].
References	[1]. Rider CF, et al. Cytokine-Induced Loss of Glucocorticoid Function: Effect of Kinase Inhibitors, Long-Acting β2-Adrenoceptor Agonist and Glucocorticoid Receptor Ligands. PLoS ONE. 2015; 10(1): e0116773. [2]. Rider, C. F., et al. TNF±-Induced Glucocorticoid Resistance: Inhibition Of Inflammatory Signalling And The Effect On Full And Partial GR Agonists. 2012

Molecular Formula	C₂₇H₁₉F₄N₃O₂S
Molecular Weight	525.51700
Exact Mass	525.11300
PSA	72.37000
LogP	7.94610

DC Chemicals Limited
China
Product Name: GSK9027
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-[4-[1-(4-Fluorophenyl)-1H-indazol-5-yl-3-(trifluoromethyl)phenyl]benzenesulfonamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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