Choline Hydroxide

Modify Date: 2024-01-02 11:42:09

Choline Hydroxide structure	Common Name	Choline Hydroxide
	CAS Number	123-41-1	Molecular Weight	121.178
	Density	1.09 g/mL at 20 °C	Boiling Point	N/A
	Molecular Formula	C₅H₁₅NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	92 °F

Use of Choline Hydroxide

Choline hydroxide is a Choline hydrogen oxidized derivative and a strong organic base, can be used as the standard alkaline to adjust the pH of the medium. Choline is an orally active nutrient, serves as an important component of lecithin and sphingomyelin, promotes fat metabolism [1][2][3].

Name	2-Hydroxyethyltrimethylammonium Hydroxide
Synonym	More Synonyms

Description	Choline hydroxide is a Choline hydrogen oxidized derivative and a strong organic base, can be used as the standard alkaline to adjust the pH of the medium. Choline is an orally active nutrient, serves as an important component of lecithin and sphingomyelin, promotes fat metabolism [1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Choline hydroxide can be used as the standard alkaline, and (0.5 M) results pHo shifts rapidly to 7.59 in a sucrose medium (pH at 7.08)[1]. Choline hydroxide (0.1-0.5 g/mL), together with organic carboxylic acids, makes preparation of ionic liquids, which is used for prepare a ionic liquid-reverse micelle drug-carrying delivery system and involves in epidermal desensitization research[2].
References	[1]. Mitchell P, et al. Estimation of membrane potential and pH difference across the cristae membrane of rat liver mitochondria. Eur J Biochem. 1969 Feb;7(4):471-84. [2]. Ding Y, et al. An ionic liquid-reverse micelle drug delivery system for epidermal desensitization therapy and its preparation method and application: China, CN113975224. 2022-01-28. [3]. Wang F, et al. Short communication: Effects of dietary deoiled soy lecithin supplementation on circulating choline and choline metabolites, and the plasma phospholipid profile in Holstein cows fed palm fat. J Dairy Sci. 2021 Feb;104(2):1838-1845.

Density	1.09 g/mL at 20 °C
Molecular Formula	C₅H₁₅NO₂
Molecular Weight	121.178
Flash Point	92 °F
Exact Mass	121.110275
PSA	43.29000
Index of Refraction	n20/D 1.4304
Storage condition	2-8°C
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility	miscible

Choline Hydroxide MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GA4025500

CHEMICAL NAME :: Choline hydroxide

CAS REGISTRY NUMBER :: 123-41-1

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C5-H14-N-O.H-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 21400 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 23,1357,1968 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1710 No. of Facilities: 31 (estimated) No. of Industries: 1 No. of Occupations: 16 No. of Employees: 11518 (estimated) No. of Female Employees: 5852 (estimated)

Hazard Codes	C:Corrosive;
Risk Phrases	R35
Safety Phrases	S26-S36/37/39-S45
RIDADR	UN 3286 3/PG 2
WGK Germany	1
RTECS	GA4025500
Packaging Group	II
Hazard Class	8
HS Code	2923900090

Precursor 10
CAS#:75-21-8 ETHYLENE OXIDE CAS#:75-50-3 Trimethylamine CAS#:17773-10-3 CHOLINE IODIDE CAS#:157-18-6 oxirene
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CAS#:108-01-0 2-(Dimethylamin... CAS#:462-10-2 4,4'-Dithiobis[...
DownStream 9
CAS#:107-21-1 Ethylene glycol CAS#:75-50-3 Trimethylamine CAS#:108-01-0 2-(Dimethylamin... CAS#:856676-23-8 Choline Fenofibrate
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CAS#:107-43-7 Betaine

HS Code	2923900090
Summary	2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide (1:1)

Bursine

Gossypine

Sincaline

VIDINE

MFCD00002831

EINECS 204-625-1

2-Hydroxy-N,N,N-trimethylethanaminium hydroxide

Luridine

Fagine

Choline hydroxide

UNII:7THJ3EG9SY

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Choline hydroxide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Choline hydroxide
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Choline hydroxide
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Choline Hydroxide

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