FUBP1-IN-2

Modify Date: 2025-08-26 06:01:20

FUBP1-IN-2 Structure
FUBP1-IN-2 structure
Common Name FUBP1-IN-2
CAS Number 1242862-71-0 Molecular Weight 479.96
Density N/A Boiling Point N/A
Molecular Formula C26H26ClN3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FUBP1-IN-2


FUBP1-IN-2 (compound 9) is a potent FUBP1 (far upstream binding protein 1) inhibitor. FUBP1-IN-2 inhibits the KH4 FUBP1-FUSE interaction in a gel shift assay. FUBP1-IN-2 binds to FUBP1 in a ChIP assay. FUBP1-IN-2 reduces both c-Myc mRNA and protein expression, increases p21 mRNA and protein expression, and depletes intracellular polyamines[1].

 Names

Name FUBP1-IN-2

 FUBP1-IN-2 Biological Activity

Description FUBP1-IN-2 (compound 9) is a potent FUBP1 (far upstream binding protein 1) inhibitor. FUBP1-IN-2 inhibits the KH4 FUBP1-FUSE interaction in a gel shift assay. FUBP1-IN-2 binds to FUBP1 in a ChIP assay. FUBP1-IN-2 reduces both c-Myc mRNA and protein expression, increases p21 mRNA and protein expression, and depletes intracellular polyamines[1].
Related Catalog
In Vitro FUBP1-IN-2 (compound 9) does not inhibit 3 H-spermidine uptake yet works synergistically with Eflornithine (HY-B0744) to limit cell growth in the presence of exogenous spermidine[1].
References

[1]. Dobrovolskaite A, et al. Discovery of Anthranilic Acid Derivatives as Difluoromethylornithine Adjunct Agents That Inhibit Far Upstream Element Binding Protein 1 (FUBP1) Function. J Med Chem. 2022 Nov 24;65(22):15391-15415.  

 Chemical & Physical Properties

Molecular Formula C26H26ClN3O4
Molecular Weight 479.96
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.