ANO1-IN-2

Modify Date: 2024-01-02 14:48:54

ANO1-IN-2 structure	Common Name	ANO1-IN-2
	CAS Number	637314-12-6	Molecular Weight	379.88
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₄ClN₃O₂S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ANO1-IN-2

ANO1-IN-2 (Compound 10q) is a selective ANO1 channel blocker with an IC50 of 1.75 μM and 7.43 μM against ANO1 and ANO2, respectively. ANO1-IN-2 suppresses strongly proliferation of glioblastoma cells[1].

Name	ANO1-IN-2

Description	ANO1-IN-2 (Compound 10q) is a selective ANO1 channel blocker with an IC50 of 1.75 μM and 7.43 μM against ANO1 and ANO2, respectively. ANO1-IN-2 suppresses strongly proliferation of glioblastoma cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> Chloride Channel
Target	IC50: 1.75 μM (ANO1), 7.43 μM (ANO2)[1]
In Vitro	ANO1-IN-2 (Compound 10q) (10 μM) significantly suppresses migration and invasion of U251 cells[1].
References	[1]. Choi SH, et al. Anti-glioma effects of 2-aminothiophene-3-carboxamide derivatives, ANO1 channel blockers. Eur J Med Chem. 2020 Dec 15;208:112688.

Molecular Formula	C₁₆H₁₄ClN₃O₂S₂
Molecular Weight	379.88