Propargyl-PEG4-C2-acid

Modify Date: 2024-01-13 11:49:28

Propargyl-PEG4-C2-acid Structure
Propargyl-PEG4-C2-acid structure
Common Name Propargyl-PEG4-C2-acid
CAS Number 1245823-51-1 Molecular Weight 304.33600
Density N/A Boiling Point N/A
Molecular Formula C14H24O7 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Propargyl-PEG4-C2-acid


Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3[1].

 Names

Name Acetylene-PEG5-acid
Synonym More Synonyms

 Propargyl-PEG4-C2-acid Biological Activity

Description Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Zhang H, et al. Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors. Bioconjug Chem. 2018 Apr 18;29(4):1266-1275.

 Chemical & Physical Properties

Molecular Formula C14H24O7
Molecular Weight 304.33600
Exact Mass 304.15200
PSA 83.45000
LogP 0.17730

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P305 + P351 + P338
Hazard Codes Xi
RIDADR NONH for all modes of transport

 Synonyms

3-(2-{2-[2-(2-prop-2-ynyloxyethoxy)ethoxy]ethoxy}ethoxy)propanoic acid
Alkyne-PEG5-acid
PROPARGYL-PEG5-ACID
Top Suppliers:I want be here


Get all suppliers and price by the below link:

Propargyl-PEG4-C2-acid suppliers

Propargyl-PEG4-C2-acid price