UNC669

Modify Date: 2024-01-11 15:52:29

UNC669 Structure
UNC669 structure
Common Name UNC669
CAS Number 1314241-44-5 Molecular Weight 338.243
Density 1.4±0.1 g/cm3 Boiling Point 458.0±45.0 °C at 760 mmHg
Molecular Formula C15H20BrN3O Melting Point N/A
MSDS N/A Flash Point 230.8±28.7 °C

 Use of UNC669


UNC 669 is a potent antagonist of L3MBTL1(IC50=4.2 uM) and L3MBTL3(IC50=3.1 uM).IC50 value: 4.2 uM/3.1 uM (L3MBTL1/L3MBTL3) [1]Target: L3MBTL1/L3MBTL3

 Names

Name Methanone, (5-​bromo-​3-​pyridinyl)​[4-​(1-​pyrrolidinyl)​-​1-​piperidinyl]​-
Synonym More Synonyms

 UNC669 Biological Activity

Description UNC 669 is a potent antagonist of L3MBTL1(IC50=4.2 uM) and L3MBTL3(IC50=3.1 uM).IC50 value: 4.2 uM/3.1 uM (L3MBTL1/L3MBTL3) [1]Target: L3MBTL1/L3MBTL3
Related Catalog
References

[1]. James LI, et al. Small-molecule ligands of methyl-lysine binding proteins: optimization of selectivity for L3MBTL3. J Med Chem. 2013 Sep 26;56(18):7358-71.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 458.0±45.0 °C at 760 mmHg
Molecular Formula C15H20BrN3O
Molecular Weight 338.243
Flash Point 230.8±28.7 °C
Exact Mass 337.078979
PSA 36.44000
LogP 1.53
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.608
Storage condition -20℃
Water Solubility Slightly soluble (6.8 g/L) (25 ºC)

 Synonyms

(5-Bromo-3-pyridinyl)[4-(1-pyrrolidinyl)-1-piperidinyl]methanone
Methanone, (5-bromo-3-pyridinyl)[4-(1-pyrrolidinyl)-1-piperidinyl]-
UNC-669
UNC 669
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