MT-3014

Modify Date: 2024-01-10 15:34:57

MT-3014 structure	Common Name	MT-3014
	CAS Number	1332727-40-8	Molecular Weight	453.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₅F₂N₇O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MT-3014

MT-3014 is a potent, highly selective and brain-penetrated phosphodiesterase 10A (PDE 10A) inhibitor, with IC50s of 0.062 nM and 0.09 nM for human PDE 10A and bovine PDE 10A, respectively[1].

Name	MT-3014

Description	MT-3014 is a potent, highly selective and brain-penetrated phosphodiesterase 10A (PDE 10A) inhibitor, with IC50s of 0.062 nM and 0.09 nM for human PDE 10A and bovine PDE 10A, respectively[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Neurological Disease
Target	human PDE 10A:0.062 nM (IC50) bovine PDE 10A:0.09 nM (IC50)
References	[1]. Koizumi Y, et al. Discovery of a pyrazolo[1,5-a]pyrimidine derivative (MT-3014) as a highly selective PDE10A inhibitor via core structure transformation from the stilbene moiety. Bioorg Med Chem. 2019 Jun 19.

Molecular Formula	C₂₃H₂₅F₂N₇O
Molecular Weight	453.49