Cbz-NH-PEG12-C2-acid

Modify Date: 2024-02-01 07:13:26

Cbz-NH-PEG12-C2-acid Structure
Cbz-NH-PEG12-C2-acid structure
Common Name Cbz-NH-PEG12-C2-acid
CAS Number 1334177-88-6 Molecular Weight 751.85594
Density N/A Boiling Point N/A
Molecular Formula C35H61NO16 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cbz-NH-PEG12-C2-acid


Cbz-NH-PEG12-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name amino-dPEG 16-acid
Synonym More Synonyms

 Cbz-NH-PEG12-C2-acid Biological Activity

Description Cbz-NH-PEG12-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C35H61NO16
Molecular Weight 751.85594

 Synonyms

CBZ-NH-PEG12-CH2CH2COOH