Cbz-NH-PEG2-CH2COOH

Modify Date: 2025-08-27 08:28:03

Cbz-NH-PEG2-CH2COOH Structure
Cbz-NH-PEG2-CH2COOH structure
Common Name Cbz-NH-PEG2-CH2COOH
CAS Number 165454-06-8 Molecular Weight 297.30400
Density N/A Boiling Point 506.6±45.0°C at 760 mmHg
Molecular Formula C14H19NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cbz-NH-PEG2-CH2COOH


Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-(phenylmethoxycarbonylamino)ethoxy]ethoxy]acetic acid
Synonym More Synonyms

 Cbz-NH-PEG2-CH2COOH Biological Activity

Description Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Boiling Point 506.6±45.0°C at 760 mmHg
Molecular Formula C14H19NO6
Molecular Weight 297.30400
Exact Mass 297.12100
PSA 97.58000
LogP 1.23500

 Safety Information

HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

AmbotzZAA1186
2-(2-(2-Benzyloxycarbonylaminoethoxy)ethoxy)acetic acid
3-Oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-oic acid
8-Benzyloxycarbonylamino-3,6-dioxaoctanoic acid
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