Methylamino-PEG3-azide

Modify Date: 2024-01-10 13:59:27

Methylamino-PEG3-azide Structure
Methylamino-PEG3-azide structure
Common Name Methylamino-PEG3-azide
CAS Number 1355197-57-7 Molecular Weight 232.280
Density N/A Boiling Point N/A
Molecular Formula C9H20N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Methylamino-PEG3-azide


Methylamino-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Methylamino-PEG3-azide
Synonym More Synonyms

 Methylamino-PEG3-azide Biological Activity

Description Methylamino-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C9H20N4O3
Molecular Weight 232.280
Exact Mass 232.153534
LogP -0.78

 Synonyms

2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-N-methylethanamine
Ethanamine, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-N-methyl-
MFCD29042356