Bromo-PEG3-azide

Modify Date: 2024-01-03 20:13:35

Bromo-PEG3-azide Structure
Bromo-PEG3-azide structure
Common Name Bromo-PEG3-azide
CAS Number 1446282-43-4 Molecular Weight 282.135
Density N/A Boiling Point N/A
Molecular Formula C8H16BrN3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG3-azide


Bromo-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-Azido-2-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}ethane
Synonym More Synonyms

 Bromo-PEG3-azide Biological Activity

Description Bromo-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H16BrN3O3
Molecular Weight 282.135
Exact Mass 281.037506
LogP 0.47

 Synonyms

Ethane, 1-(2-azidoethoxy)-2-[2-(2-bromoethoxy)ethoxy]-
1-Azido-2-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}ethane
Bromo-PEG3-azide
Bromo-PEG4-azide
1-Azido-2-(2-[2-(2-bromoethoxy)ethoxy]ethoxy)ethane
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