polymyxin B2
Modify Date: 2025-08-22 19:59:43
polymyxin B2 structure
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Common Name | polymyxin B2 | ||
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| CAS Number | 1404-26-8 | Molecular Weight | 1189.450 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 1572.3±65.0 °C at 760 mmHg | |
| Molecular Formula | C55H96N16O13 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 904.7±34.3 °C | |
Use of polymyxin B2Polymyxin B is an antibiotic. Polymyxin B inhibits Gram-negative infections by binding to the LPS of the bacterial wall with high affinity. Polymyxin B neutralizes the effect of endotoxin. Polymyxin B induces bacterial death by increasing its permeability. Polymyxin B is used in endotoxemia research[1][3]. |
| Name | polymyxin B2 |
|---|---|
| Synonym | More Synonyms |
| Description | Polymyxin B is an antibiotic. Polymyxin B inhibits Gram-negative infections by binding to the LPS of the bacterial wall with high affinity. Polymyxin B neutralizes the effect of endotoxin. Polymyxin B induces bacterial death by increasing its permeability. Polymyxin B is used in endotoxemia research[1][3]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 1572.3±65.0 °C at 760 mmHg |
| Molecular Formula | C55H96N16O13 |
| Molecular Weight | 1189.450 |
| Flash Point | 904.7±34.3 °C |
| Exact Mass | 1188.734253 |
| PSA | 490.66000 |
| LogP | -3.40 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.593 |
| Heptanamide, N-[(1S)-3-amino-1-[[[(1S,2R)-1-[[[(1S)-3-amino-1-[[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-15-(phenylmethyl)-1,4,7,10,13,16,19-heptaazacyclotricos-21-yl]amino]carbonyl]propyl]amino]carbonyl]-2-hydroxypropyl]amino]carbonyl]propyl]-6-methyl- |
| polymyxin B2 |
| N-[(2S)-4-Amino-1-{[(2S,3R)-1-{[(2S)-4-amino-1-oxo-1-({(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl}amino)-2-butanyl]amino}-3-hydroxy-1-oxo-2-butanyl]amino}-1-oxo-2-butanyl]-6-methylheptanamide |