Polymyxin B nonapeptide TFA
Modify Date: 2024-01-16 17:35:40
Polymyxin B nonapeptide TFA structure
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Common Name | Polymyxin B nonapeptide TFA | ||
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| CAS Number | 2220175-42-6 | Molecular Weight | 1533.25 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C43H74N14O11.5C2HF3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Polymyxin B nonapeptide TFAPolymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue[1]. Polymyxin B nonapeptide TFA is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes[2]. |
| Name | Polymyxin B nonapeptide TFA |
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| Description | Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue[1]. Polymyxin B nonapeptide TFA is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes[2]. |
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| Related Catalog | |
| In Vitro | Polymyxin B nonapeptide, a cationic cyclic peptide derived by enzymatic processing from the naturally occurring peptide polymyxin B, is able to increase the permeability of the outer membrane of Gram-negative bacteria toward hydrophobic antibiotics probably by binding to the bacterial lipopolysaccharide (LPS)[1]. |
| References |
| Molecular Formula | C43H74N14O11.5C2HF3O2 |
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| Molecular Weight | 1533.25 |
| Hazard Codes | Xi |
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