m-PEG4-NHS ester structure
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Common Name | m-PEG4-NHS ester | ||
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CAS Number | 622405-78-1 | Molecular Weight | 333.334 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 431.7±55.0 °C at 760 mmHg | |
Molecular Formula | C14H23NO8 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 214.9±31.5 °C |
Use of m-PEG4-NHS esterm-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]propanoate |
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Synonym | More Synonyms |
Description | m-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
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Related Catalog | |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 431.7±55.0 °C at 760 mmHg |
Molecular Formula | C14H23NO8 |
Molecular Weight | 333.334 |
Flash Point | 214.9±31.5 °C |
Exact Mass | 333.142365 |
PSA | 100.60000 |
LogP | -2.87 |
Vapour Pressure | 0.0±1.0 mmHg at 25°C |
Index of Refraction | 1.490 |
Storage condition | -20°C |
~70% m-PEG4-NHS ester CAS#:622405-78-1 |
Literature: BIOCON LIMITED Patent: US2011/118480 A1, 2011 ; Location in patent: Page/Page column 5 ; |
~% m-PEG4-NHS ester CAS#:622405-78-1 |
Literature: BIOCON LIMITED Patent: US2011/118480 A1, 2011 ; |
~% m-PEG4-NHS ester CAS#:622405-78-1 |
Literature: BIOCON LIMITED Patent: US2011/118480 A1, 2011 ; |
Precursor 3 | |
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DownStream 0 |
N-Succinimidyl 4,7,10,13-Tetraoxatetradecanoate |
1-[(14-Oxo-2,5,8,11-tetraoxatetradecan-14-yl)oxy]-2,5-pyrrolidinedione |
Methyl-PEG4-NHS Ester |
4,7,10,13-Tetraoxatetradecanoic Acid N-Succinimidyl Ester |
2,5-Pyrrolidinedione, 1-[(1-oxo-4,7,10,13-tetraoxatetradec-1-yl)oxy]- |
AmbotzPEG1880 |
1-(4,7,10,13-tetraoxatetradecan-1-oyloxy)pyrrolidine-2,5-dione |
N-hydroxysuccinimidyl 3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-propanoate |
M2186 |