3,4-Dimethoxycinnamic acid

Modify Date: 2024-01-05 10:04:07

3,4-Dimethoxycinnamic acid structure	Common Name	3,4-Dimethoxycinnamic acid
	CAS Number	14737-89-4	Molecular Weight	208.211
	Density	1.2±0.1 g/cm3	Boiling Point	367.4±27.0 °C at 760 mmHg
	Molecular Formula	C₁₁H₁₂O₄	Melting Point	181-183ºC(lit.)
	MSDS	N/A	Flash Point	144.0±17.2 °C

Use of 3,4-Dimethoxycinnamic acid

(E)-3,4-Dimethoxycinnamic acid is the less active isomer of 3,4-Dimethoxycinnamic acid. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway[1]. Anti-apoptotic effects[1].

Name	3,4-dimethoxycinnamic acid
Synonym	More Synonyms

Description	(E)-3,4-Dimethoxycinnamic acid is the less active isomer of 3,4-Dimethoxycinnamic acid. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway[1]. Anti-apoptotic effects[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection
In Vitro	3,4-Dimethoxycinnamic acid (Methyl ferulic acid; 25, 50 and 100 µM) attenuates the ethanol-induced apoptosis of ethanolexposed L-02 cells[1]. 3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) inhibits the expression levels of Nox4 and p22phox in L-02 cells[1]. 3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) treatment attenuates ethanol-induced MAPK phosphorylation in L-02 cells[1]. 3,4-Dimethoxycinnamic acid decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase, and downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner[1].
References	[1]. Li L, et al. Methyl ferulic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signalingpathway. Int J Oncol. 2018 Jul;53(1):225-236.

Density	1.2±0.1 g/cm3
Boiling Point	367.4±27.0 °C at 760 mmHg
Melting Point	181-183ºC(lit.)
Molecular Formula	C₁₁H₁₂O₄
Molecular Weight	208.211
Flash Point	144.0±17.2 °C
Exact Mass	208.073563
PSA	55.76000
LogP	2.24
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.574

Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	37/39-26
WGK Germany	3

Precursor 10
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