2-Iodoadenosine

Modify Date: 2025-08-23 16:47:18

2-Iodoadenosine Structure
2-Iodoadenosine structure
Common Name 2-Iodoadenosine
CAS Number 35109-88-7 Molecular Weight 393.14
Density 2.7±0.1 g/cm3 Boiling Point 776.3±70.0 °C at 760 mmHg
Molecular Formula C10H12IN5O4 Melting Point 200ºC (dec.)
MSDS N/A Flash Point 423.3±35.7 °C

 Use of 2-Iodoadenosine


2-Iodoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

 Names

Name (2R,3R,4S,5R)-2-(6-amino-2-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Synonym More Synonyms

 2-Iodoadenosine Biological Activity

Description 2-Iodoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

 Chemical & Physical Properties

Density 2.7±0.1 g/cm3
Boiling Point 776.3±70.0 °C at 760 mmHg
Melting Point 200ºC (dec.)
Molecular Formula C10H12IN5O4
Molecular Weight 393.14
Flash Point 423.3±35.7 °C
Exact Mass 392.993378
PSA 139.54000
LogP -1.04
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.994
Storage condition Refrigerator, Under Inert Atmosphere

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26

 Synthetic Route

 Synonyms

2-iodo-2',3'-O-isopropylidene-adenosine
Adenosine,2-iodo
MFCD01320413
2-idodadenosine
6-Amino-2-iodo-9-(β-D-ribofuranosyl)purine
2-Iodoadenosine
2-Iodo-D-adenosine
Adenosine, 2-iodo-
2-IODO ADENOSINE
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