JKA3 inhibitor 31
Modify Date: 2024-01-18 21:57:37
JKA3 inhibitor 31 structure
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Common Name | JKA3 inhibitor 31 | ||
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| CAS Number | 1637749-82-6 | Molecular Weight | 288.31 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H12N4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JKA3 inhibitor 31JKA3 inhibitor 31 is a highly potent, selective, reversible, covalent JAK3 inhibitor with IC50 of 49 nM, shows no activity against other JAK kinases; also inhibits BLK, ERB-B4 and ITK with IC50 of 22 nM, 44 nM and 221 nM, respectively. |
| Name | JKA3 inhibitor 31 |
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| Description | JKA3 inhibitor 31 is a highly potent, selective, reversible, covalent JAK3 inhibitor with IC50 of 49 nM, shows no activity against other JAK kinases; also inhibits BLK, ERB-B4 and ITK with IC50 of 22 nM, 44 nM and 221 nM, respectively. |
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| References | References 1. London N, et al. Nat Chem Biol. 2014 Dec;10(12):1066-72. 2. Clark JD, et al. J Med Chem. 2014 Jun 26;57(12):5023-38. View Related Products by Target JAK |
| Molecular Formula | C17H12N4O |
|---|---|
| Molecular Weight | 288.31 |