sPLA2-X inhibitor 31

Modify Date: 2024-01-20 13:31:17

sPLA2-X inhibitor 31 Structure
sPLA2-X inhibitor 31 structure
Common Name sPLA2-X inhibitor 31
CAS Number 2241025-50-1 Molecular Weight 392.33
Density N/A Boiling Point N/A
Molecular Formula C19H15F3N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of sPLA2-X inhibitor 31


sPLA2-X Inhibitor 31 is a selective secreted phospholipase A2 type X (sPLA2-X) inhibitor with IC50s of 26 nM, 310 nM, and 2230 nM for sPLA2-X, sPLA2-IIa, and sPLA2-V, respectively[1].

 Names

Name sPLA2-X Inhibitor 31

 sPLA2-X inhibitor 31 Biological Activity

Description sPLA2-X Inhibitor 31 is a selective secreted phospholipase A2 type X (sPLA2-X) inhibitor with IC50s of 26 nM, 310 nM, and 2230 nM for sPLA2-X, sPLA2-IIa, and sPLA2-V, respectively[1].
Related Catalog
Target

IC50: 26 nM (sPLA2 -X), 310nM (sPLA2-IIa), 2230 nM (sPLA2-V)[1]

References

[1]. Knerr L, et al. Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X(sPLA2-X) Inhibitors. ACS Med Chem Lett. 2018 Jun 23;9(7):594-599.

 Chemical & Physical Properties

Molecular Formula C19H15F3N2O4
Molecular Weight 392.33