MC-100093

Modify Date: 2023-01-16 10:41:51

MC-100093 Structure
MC-100093 structure
Common Name MC-100093
CAS Number 1639784-02-3 Molecular Weight 269.345
Density N/A Boiling Point N/A
Molecular Formula C13H23N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MC-100093


MC-100093 (MC100093) is a potent, orally bioavailable upregulator of GLT-1 and devoid of antimicrobial properties.MC-100093 enhanced uptake of glutamate into astrocytes in a mouse neuron/astrocyte co-culture model with IC50 of 0.1 uM.MC-100093 restored the expression of NA core GLT-1.MC-100093 (50 mg/kg) attenuated cue-primed relapse to cocaine-seeking without reducing motivation to consume regular chow or sucrose pellets or affecting body weight.

 Names

Name MC-100093

 MC-100093 Biological Activity

Description MC-100093 (MC100093) is a potent, orally bioavailable upregulator of GLT-1 and devoid of antimicrobial properties.MC-100093 enhanced uptake of glutamate into astrocytes in a mouse neuron/astrocyte co-culture model with IC50 of 0.1 uM.MC-100093 restored the expression of NA core GLT-1.MC-100093 (50 mg/kg) attenuated cue-primed relapse to cocaine-seeking without reducing motivation to consume regular chow or sucrose pellets or affecting body weight.
References 1. Lori A Knackstedt, et al. J Pharmacol Exp Ther. 2021 Aug;378(2):51-59.

 Chemical & Physical Properties

Molecular Formula C13H23N3O3
Molecular Weight 269.345