![]() MC-100093 structure
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Common Name | MC-100093 | ||
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CAS Number | 1639784-02-3 | Molecular Weight | 269.345 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C13H23N3O3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of MC-100093MC-100093 (MC100093) is a potent, orally bioavailable upregulator of GLT-1 and devoid of antimicrobial properties.MC-100093 enhanced uptake of glutamate into astrocytes in a mouse neuron/astrocyte co-culture model with IC50 of 0.1 uM.MC-100093 restored the expression of NA core GLT-1.MC-100093 (50 mg/kg) attenuated cue-primed relapse to cocaine-seeking without reducing motivation to consume regular chow or sucrose pellets or affecting body weight. |
Name | MC-100093 |
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Description | MC-100093 (MC100093) is a potent, orally bioavailable upregulator of GLT-1 and devoid of antimicrobial properties.MC-100093 enhanced uptake of glutamate into astrocytes in a mouse neuron/astrocyte co-culture model with IC50 of 0.1 uM.MC-100093 restored the expression of NA core GLT-1.MC-100093 (50 mg/kg) attenuated cue-primed relapse to cocaine-seeking without reducing motivation to consume regular chow or sucrose pellets or affecting body weight. |
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References | 1. Lori A Knackstedt, et al. J Pharmacol Exp Ther. 2021 Aug;378(2):51-59. |
Molecular Formula | C13H23N3O3 |
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Molecular Weight | 269.345 |