PI3Kβ and δ inhibitor 20a
Modify Date: 2024-01-11 06:47:37
PI3Kβ and δ inhibitor 20a structure
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Common Name | PI3Kβ and δ inhibitor 20a | ||
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| CAS Number | 1842380-77-1 | Molecular Weight | 450.26 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H14Cl2FN9O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PI3Kβ and δ inhibitor 20aPI3K-IN-6 (compound 20a) is an oral active and highly selective phosphoinositide 3-kinase (PI3K) β/δ inhibitor, with IC50 values of 7.8 nM/5.3 nM for PI3K β/δ, respectively. PI3K-IN-6 (compound 20a) has potential top treat phosphatase and tensin homolog (PTEN) feficient tumors[1]. |
| Name | PI3K-IN-6 |
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| Description | PI3K-IN-6 (compound 20a) is an oral active and highly selective phosphoinositide 3-kinase (PI3K) β/δ inhibitor, with IC50 values of 7.8 nM/5.3 nM for PI3K β/δ, respectively. PI3K-IN-6 (compound 20a) has potential top treat phosphatase and tensin homolog (PTEN) feficient tumors[1]. |
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| Related Catalog | |
| Target |
PI3Kβ:7.8 nM (IC50) PI3Kδ:5.3 nM (IC50) PI3Kα:850 nM (IC50) |
| References |
| Molecular Formula | C17H14Cl2FN9O |
|---|---|
| Molecular Weight | 450.26 |