BCR-ABL-IN-1

Modify Date: 2024-01-17 15:19:59

BCR-ABL-IN-1 Structure
BCR-ABL-IN-1 structure
Common Name BCR-ABL-IN-1
CAS Number 188260-50-6 Molecular Weight 459.44
Density N/A Boiling Point N/A
Molecular Formula C23H21F4N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BCR-ABL-IN-1


BCR-ABL-IN-1 is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia.

 Names

Name BCR-ABL-IN-1

 BCR-ABL-IN-1 Biological Activity

Description BCR-ABL-IN-1 is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia.
Related Catalog
Target

pIC50: 6.46 (BCR-ABL)[1]

In Vitro BCR-ABL-IN-1 (Compound 21) is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia.
References

[1]. Cui J1, et al. BCR-ABL tyrosine kinase inhibitor pharmacophore model derived from a series of phenylaminopyrimidine-based (PAP) derivatives. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2442-50.

 Chemical & Physical Properties

Molecular Formula C23H21F4N5O
Molecular Weight 459.44
Storage condition 2-8℃