BCR-ABL-IN-4

Modify Date: 2025-08-24 22:33:10

BCR-ABL-IN-4 Structure
BCR-ABL-IN-4 structure
Common Name BCR-ABL-IN-4
CAS Number 2669790-59-2 Molecular Weight 555.96
Density N/A Boiling Point N/A
Molecular Formula C27H24ClF2N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BCR-ABL-IN-4


BCR-ABL-IN-4 is a BCR-ABL inhibitor with anticancer effects. BCR-ABL-IN-4 inhibits the cancer cell growth with IC50 values of 0.67 nM and 16 nM for K562 cells and BCR-ABL T315I transfected Ba/F3 cells, respectively (WO2021143927A1; compound 11)[1].

 Names

Name BCR-ABL-IN-4

 BCR-ABL-IN-4 Biological Activity

Description BCR-ABL-IN-4 is a BCR-ABL inhibitor with anticancer effects. BCR-ABL-IN-4 inhibits the cancer cell growth with IC50 values of 0.67 nM and 16 nM for K562 cells and BCR-ABL T315I transfected Ba/F3 cells, respectively (WO2021143927A1; compound 11)[1].
Related Catalog
References

[1]. Yinsheng Zhang, et al. Compound acting as bcr-abl inhibitor. WO2021143927A1.

 Chemical & Physical Properties

Molecular Formula C27H24ClF2N5O4
Molecular Weight 555.96
InChIKey YKODBSQOEOUPRJ-LJQANCHMSA-N
SMILES O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCC(O)C2)c(-c2cnc3c(c2)C(=O)N(C2CC2)C3)c1
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