MMP-9/MMP-13 INHIBITOR I

Modify Date: 2024-01-03 18:34:46

MMP-9/MMP-13 INHIBITOR I Structure
MMP-9/MMP-13 INHIBITOR I structure
Common Name MMP-9/MMP-13 INHIBITOR I
CAS Number 204140-01-2 Molecular Weight 495.55
Density N/A Boiling Point N/A
Molecular Formula C25H25N3O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MMP-9/MMP-13 INHIBITOR I


MMP-9/MMP-13 Inhibitor I is a potent MMP-9 and MMP-13 inhibitor with IC50s of both 0.9 nM. MMP-9/MMP-13 Inhibitor I shows >20-folds selectivity for MMP-9/MMP-13 over other MMPs[1].

 Names

Name MMP-9/MMP-13 INHIBITOR I

 MMP-9/MMP-13 INHIBITOR I Biological Activity

Description MMP-9/MMP-13 Inhibitor I is a potent MMP-9 and MMP-13 inhibitor with IC50s of both 0.9 nM. MMP-9/MMP-13 Inhibitor I shows >20-folds selectivity for MMP-9/MMP-13 over other MMPs[1].
Related Catalog
Target

MMP-9:0.9 nM (IC50)

MMP-13:0.9 nM (IC50)

MMP-1:43 nM (IC50)

MMP-3:23 nM (IC50)

MMP-7:931 nM (IC50)

In Vitro MMP-9/MMP-13 Inhibitor I (化合物 35) 抑制 MMP-1、MMP-3 和 MMP-7,IC50 值分别为 43 nM、23 nM 和 931 nM[1]。
References

[1]. M Cheng, et al. Design and synthesis of piperazine-based matrix metalloproteinase inhibitors. J Med Chem. 2000 Feb 10;43(3):369-80.  

 Chemical & Physical Properties

Molecular Formula C25H25N3O6S
Molecular Weight 495.55
Storage condition -20°C