JAK-IN-24

Modify Date: 2025-08-26 14:15:19

JAK-IN-24 structure	Common Name	JAK-IN-24
	CAS Number	2042629-43-4	Molecular Weight	367.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₅N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of JAK-IN-24

JAK-IN-24 is a JAK inhibitor, with IC50s of 0.534 and 24 nM at the presence of 4 μM or 1mM ATP, respectively. JAK-IN-24 also inhibits PBMC IL-15 induced STAT5 phosphorylation with an IC50 of 86.171 nM[1].

Name	JAK-IN-24

Description	JAK-IN-24 is a JAK inhibitor, with IC50s of 0.534 and 24 nM at the presence of 4 μM or 1mM ATP, respectively. JAK-IN-24 also inhibits PBMC IL-15 induced STAT5 phosphorylation with an IC50 of 86.171 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Research Areas >> Inflammation/Immunology
In Vitro	JAK-IN-24 (Example 129) 在 4 μM 或 1mM ATP 存在时抑制 JAK 的 IC50 值分别为 0.534 和 24 nM[1]。 JAK-IN-24 在人全血中表现出稳定性，t1/2 为 267.223 分钟[1]。 JAK-IN-24 抑制 PBMC IL-15 诱导的 STAT5 磷酸化，IC50 为 86.171 nM[1]。
References	[1]. Atli Thorarensen, et al. Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl, pyrrolo[2,3-b]pyridinyl acrylamides and epoxides thereof. Patent. WO2016178110.

Molecular Formula	C₂₀H₂₅N₅O₂
Molecular Weight	367.44

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com