Mal-amido-(CH2COOH)2
Modify Date: 2025-09-20 06:23:04
Mal-amido-(CH2COOH)2 structure
|
Common Name | Mal-amido-(CH2COOH)2 | ||
|---|---|---|---|---|
| CAS Number | 207613-14-7 | Molecular Weight | 284.22 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H12N2O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Mal-amido-(CH2COOH)2Mal-amido-(CH2COOH)2, compound 7a, is a maleimidoethyl-containing intermediate for hydrophilic ADC linker[1]. |
| Name | Mal-amido-(CH2COOH)2 |
|---|
| Description | Mal-amido-(CH2COOH)2, compound 7a, is a maleimidoethyl-containing intermediate for hydrophilic ADC linker[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | Mal-amido-(CH2COOH)2 is a intermediate for linker. Bivalent doxorubicin (DOX)-dipeptides (16a-c) are finally prepared and conjugated to the monoclonal antibody BR96. The dipeptides are cleaved by lysosomal proteases following internalization of the resulting immunoconjugates[1]. |
| In Vivo | ADC Linker |
| References |
| Molecular Formula | C11H12N2O7 |
|---|---|
| Molecular Weight | 284.22 |