CXCR4 probe 1

Modify Date: 2024-01-19 19:50:51

CXCR4 probe 1 Structure
CXCR4 probe 1 structure
 Common Name CXCR4 probe 1
CAS Number 2077985-50-1 Molecular Weight 502.59
Density N/A Boiling Point N/A
Molecular Formula C24H3018FN5O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CXCR4 probe 1


CXCR4 probe 1 (compound 5) is a potent and specific CXCR4-targeted PET tracer with an IC50 value of 6.9 nM against CXCR4-specific antagonist peptide, TN14003. CXCR4 probe 1 has potential to be used as CXCR4-specific imaging probe to diagnose and monitor the prognosis of inflammatory diseases, CXCR4-positive tumors, and metastatic cancers[1].

 Names

Name CXCR4 probe 1

 CXCR4 probe 1 Biological Activity

Description CXCR4 probe 1 (compound 5) is a potent and specific CXCR4-targeted PET tracer with an IC50 value of 6.9 nM against CXCR4-specific antagonist peptide, TN14003. CXCR4 probe 1 has potential to be used as CXCR4-specific imaging probe to diagnose and monitor the prognosis of inflammatory diseases, CXCR4-positive tumors, and metastatic cancers[1].
Related Catalog
Target

CXCR4

In Vivo CXCR4 probe 1 displays preferential accumulation in lung metastatic tumors and specifically binds to CXCR4-positive stem cells in bone marrow[1].
References

[1]. Oum YH, et al. A benzenesulfonamide derivative as a novel PET radioligand for CXCR4. Bioorg Med Chem. 2020 Jan 15;28(2):115240.

 Chemical & Physical Properties

Molecular Formula C24H3018FN5O4S
Molecular Weight 502.59
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Chemsrc provides CXCR4 probe 1(CAS#:2077985-50-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of CXCR4 probe 1 are included as well.>> amp version: CXCR4 probe 1

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