PROTAC RIPK degrader-6
Modify Date: 2024-01-19 10:48:52
PROTAC RIPK degrader-6 structure
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Common Name | PROTAC RIPK degrader-6 | ||
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| CAS Number | 2089205-64-9 | Molecular Weight | 889.00 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C43H48N6O11S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PROTAC RIPK degrader-6PROTAC RIPK degrader-6 (example 1) is a PROTAC targeting RIP Kinase degradation wherein the RIP2 kinase inhibitor is linked via a linker to a cereblon binder[1]. |
| Name | PROTAC RIPK degrader-6 |
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| Description | PROTAC RIPK degrader-6 (example 1) is a PROTAC targeting RIP Kinase degradation wherein the RIP2 kinase inhibitor is linked via a linker to a cereblon binder[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs is useful for the targeted degradation of proteins and other polypeptides which on the one end binds to the cereblon and on the other end to the target protein (RIP2 kinase). By bringing the target protein in close proximity to the E3-Ligase, these compounds form a ternary complex leading to polyubiquitination of the target protein inducing its degradation[1]. |
| References |
[1]. John David Harlin, et al. Compounds for the modulation of rip2 kinase activity. WO2017046036A1. |
| Molecular Formula | C43H48N6O11S2 |
|---|---|
| Molecular Weight | 889.00 |
| Storage condition | -20°C |