Thalidomide-PEG4-Propargyl
Modify Date: 2024-01-14 18:47:33
Thalidomide-PEG4-Propargyl structure
|
Common Name | Thalidomide-PEG4-Propargyl | ||
|---|---|---|---|---|
| CAS Number | 2098799-77-8 | Molecular Weight | 488.49 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H28N2O9 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thalidomide-PEG4-PropargylThalidomide-PEG4-Propargyl is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
| Name | Thalidomide-PEG4-Propargyl |
|---|
| Description | Thalidomide-PEG4-Propargyl is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
|---|---|
| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C24H28N2O9 |
|---|---|
| Molecular Weight | 488.49 |
| Hazard Codes | Xi |
|---|