Aminooxy-PEG1-azide

Modify Date: 2024-01-14 20:29:20

Aminooxy-PEG1-azide Structure
Aminooxy-PEG1-azide structure
Common Name Aminooxy-PEG1-azide
CAS Number 2100306-70-3 Molecular Weight 146.15
Density N/A Boiling Point N/A
Molecular Formula C4H10N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aminooxy-PEG1-azide


Aminooxy-PEG1-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Aminooxy-PEG1-azide

 Aminooxy-PEG1-azide Biological Activity

Description Aminooxy-PEG1-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

 Chemical & Physical Properties

Molecular Formula C4H10N4O2
Molecular Weight 146.15
Storage condition 2-8°C