Aminooxy-PEG1-propargyl HCl

Modify Date: 2024-01-09 15:22:12

Aminooxy-PEG1-propargyl HCl Structure
Aminooxy-PEG1-propargyl HCl structure
Common Name Aminooxy-PEG1-propargyl HCl
CAS Number 1895922-69-6 Molecular Weight 115.13
Density N/A Boiling Point N/A
Molecular Formula C5H9NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aminooxy-PEG1-propargyl HCl


Aminooxy-PEG1-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Aminooxy-PEG1-propargyl

 Aminooxy-PEG1-propargyl HCl Biological Activity

Description Aminooxy-PEG1-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

 Chemical & Physical Properties

Molecular Formula C5H9NO2
Molecular Weight 115.13
Storage condition 2-8°C
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