Pomalidomide-PEG1-azide

Modify Date: 2024-07-19 10:09:11

Pomalidomide-PEG1-azide Structure
Pomalidomide-PEG1-azide structure
Common Name Pomalidomide-PEG1-azide
CAS Number 2133360-04-8 Molecular Weight 400.35
Density N/A Boiling Point N/A
Molecular Formula C17H16N6O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pomalidomide-PEG1-azide


Pomalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Pomalidomide-PEG1-azide incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-1 (HY-133131)[1].

 Names

Name Pomalidomide-PEG1-azide

 Pomalidomide-PEG1-azide Biological Activity

Description Pomalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Pomalidomide-PEG1-azide incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-1 (HY-133131)[1].
Related Catalog
References

[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

 Chemical & Physical Properties

Molecular Formula C17H16N6O6
Molecular Weight 400.35

 Safety Information

Hazard Codes Xi
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