Pomalidomide-PEG1-azide

Modify Date: 2023-01-21 21:17:51

Pomalidomide-PEG1-azide structure	Common Name	Pomalidomide-PEG1-azide
	CAS Number	2133360-04-8	Molecular Weight	400.35
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₆N₆O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Pomalidomide-PEG1-azide

Pomalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Pomalidomide-PEG1-azide incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-1 (HY-133131)[1].

Name	Pomalidomide-PEG1-azide

Description	Pomalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Pomalidomide-PEG1-azide incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-1 (HY-133131)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
References	[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

Molecular Formula	C₁₇H₁₆N₆O₆
Molecular Weight	400.35

Hazard Codes	Xi

Pomalidomide-PEG1-azide

Use of Pomalidomide-PEG1-azide

Names

Pomalidomide-PEG1-azide Biological Activity

Chemical & Physical Properties

Safety Information