Lenalidomide-PEG1-azide

Modify Date: 2024-01-10 23:07:16

Lenalidomide-PEG1-azide structure	Common Name	Lenalidomide-PEG1-azide
	CAS Number	2185795-67-7	Molecular Weight	386.36
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₈N₆O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Lenalidomide-PEG1-azide

Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 (HY-133136)[1].

Name	Lenalidomide-PEG1-azide

Description	Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 (HY-133136)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
References	[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

Molecular Formula	C₁₇H₁₈N₆O₅
Molecular Weight	386.36

Hazard Codes	Xi

Lenalidomide-PEG1-azide

Use of Lenalidomide-PEG1-azide

Names

Lenalidomide-PEG1-azide Biological Activity

Chemical & Physical Properties

Safety Information