Azido-PEG5-succinimidyl carbonate

Modify Date: 2024-01-07 20:09:10

Azido-PEG5-succinimidyl carbonate Structure
Azido-PEG5-succinimidyl carbonate structure
Common Name Azido-PEG5-succinimidyl carbonate
CAS Number 1402411-88-4 Molecular Weight 448.43
Density N/A Boiling Point N/A
Molecular Formula C17H28N4O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG5-succinimidyl carbonate


Azido-PEG5-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG5-succinimidyl carbonate

 Azido-PEG5-succinimidyl carbonate Biological Activity

Description Azido-PEG5-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C17H28N4O10
Molecular Weight 448.43