m-PEG3-succinimidyl carbonate

Modify Date: 2024-01-10 17:28:31

m-PEG3-succinimidyl carbonate structure	Common Name	m-PEG3-succinimidyl carbonate
	CAS Number	477775-77-2	Molecular Weight	305.28100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₉NO₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of m-PEG3-succinimidyl carbonate

m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	2,5-dioxopyrrolidin-1-yl (2-(2-(2-methoxyethoxy)ethoxy)ethyl)carbonate
Synonym	More Synonyms

Description	m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Miller MA, et al. Amphiphilic conjugates of human brain natriuretic peptide designed for oral delivery: in vitro activity screening. Bioconjug Chem. 2006 Mar-Apr;17(2):267-74.

8-methoxy-3,6-dioxaoctyl N-succinimidyl carbonate

carbonic acid 2,5-dioxo-pyrrolidin-1-yl ester 2-[2-(2-methoxy-ethoxy)-ethoxy]-ethyl ester

activated triethylene glycol monomethyl oligomer

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