CU CPT 9a
Modify Date: 2024-02-28 09:51:22
CU CPT 9a structure
|
Common Name | CU CPT 9a | ||
|---|---|---|---|---|
| CAS Number | 2165340-32-7 | Molecular Weight | 265.3065 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H15NO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CU CPT 9aCU-CPT-9a is a specific TLR8 antagonist, with an IC50 of 0.5 nM. |
| Name | 4-(7-methoxyquinolin-4-yl)-2-methylphenol |
|---|---|
| Synonym | More Synonyms |
| Description | CU-CPT-9a is a specific TLR8 antagonist, with an IC50 of 0.5 nM. |
|---|---|
| Related Catalog | |
| Target |
TLR8:0.5 nM (IC50) |
| In Vitro | CU-CPT-9a is a specific TLR8 antagonist, with an IC50 of 0.5±0.1 nM. The elevation of the downstream protein levels induced by R848 can be reversed by CU-CPT-9a in a dose-dependent manner. By contrast, the expression of TRIF and IRF3 (cytoplasmic and nuclear) are only responsive to TLR4 and TLR3, independent of TLR837. The expression levels of TRIF and IRF3 do not show significant change in THP-1 cells upon treatment of R848, nor do they change with the treatment of CU-CPT-9a. CU-CPT8m and CU-CPT-9a both significantly suppress the TNF-α level in a dose-dependent manner, which is in agreement with previous reports of TLR8 involvement in these autoimmune diseases[1]. |
| References |
| Molecular Formula | C17H15NO2 |
|---|---|
| Molecular Weight | 265.3065 |
| Storage condition | 2-8℃ |
| CU-CPT-9B |
| CPD2004 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: CU CPT 9a
- Price: Negotiable
- Purity: 99.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: CU-CPT-9a
- Price: $550.0/100mg $1000.0/250mg $1900.0/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: CU-CPT-9a
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 4-(7-methoxyquinolin-4-yl)-2-methylphenol
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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Price: ￥1650/10 mM * 1 mL in DMSO
Reference only. check more CU CPT 9a price