Bis-Tos-PEG6

Modify Date: 2024-01-08 01:54:20

Bis-Tos-PEG6 Structure
Bis-Tos-PEG6 structure
 Common Name Bis-Tos-PEG6
CAS Number 42749-27-9 Molecular Weight 590.70300
Density 1.24g/cm3 Boiling Point 687.4ºC at 760 mmHg
Molecular Formula C26H38O11S2 Melting Point N/A
MSDS Chinese USA Flash Point 369.5ºC

 Use of Bis-Tos-PEG6


Bis-Tos-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
Synonym More Synonyms

 Bis-Tos-PEG6 Biological Activity

Description Bis-Tos-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.24g/cm3
Boiling Point 687.4ºC at 760 mmHg
Molecular Formula C26H38O11S2
Molecular Weight 590.70300
Flash Point 369.5ºC
Exact Mass 590.18600
PSA 149.65000
LogP 4.65880
Index of Refraction 1.525

 Safety Information

RIDADR NONH for all modes of transport
HS Code 2909499000

 Customs

HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

PEG7-bis-Tos
Hexaethylene glycol ditosylate
O,O'-ditosyl-3,6,9,12,15-pentaoxaheptadecane-1,17-diol
3,6,9,12,15-pentaoxaheptadecane-1,17-diol ditosylate
HEG ditosylate
3,6,9,12,15-pentaoxa-1,17-heptadecyl di-p-toluenesulfonate
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Chemsrc provides Bis-Tos-PEG6(CAS#:42749-27-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Bis-Tos-PEG6 are included as well.>> amp version: Bis-Tos-PEG6

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