Sirt2-IN-6

Modify Date: 2024-01-10 18:48:10

Sirt2-IN-6 Structure
Sirt2-IN-6 structure
Common Name Sirt2-IN-6
CAS Number 2243151-81-5 Molecular Weight 502.59
Density N/A Boiling Point N/A
Molecular Formula C26H26N6O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Sirt2-IN-6


Sirt2-IN-6 (compound 24a) potent and selective inhibitor of SIRT2, with an IC50 of 0.815 μM. Sirt2-IN-6 can be used for the research of cancer[1].

 Names

Name Sirt2-IN-6

 Sirt2-IN-6 Biological Activity

Description Sirt2-IN-6 (compound 24a) potent and selective inhibitor of SIRT2, with an IC50 of 0.815 μM. Sirt2-IN-6 can be used for the research of cancer[1].
Related Catalog
Target

SIRT2:0.815 μM (IC50)

References

[1]. Yang LL, et, al. X-ray crystal structure guided discovery of new selective, substrate-mimicking sirtuin 2 inhibitors that exhibit activities against non-small cell lung cancer cells. Eur J Med Chem. 2018 Jul 15;155:806-823.

 Chemical & Physical Properties

Molecular Formula C26H26N6O3S
Molecular Weight 502.59