MB 0223
Modify Date: 2024-01-16 12:24:02
MB 0223 structure
|
Common Name | MB 0223 | ||
|---|---|---|---|---|
| CAS Number | 2247732-89-2 | Molecular Weight | 457.59 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H27N5OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MB 0223MB-0223 is a potent and selective dynamin-related GTPase Drp1 partial inhibitor (IC50=1.3 μM) over other dynamin family members, Opa 1 and dynamin-1 (IC50>100 μM)[1]. |
| Name | MB-0223 |
|---|
| Description | MB-0223 is a potent and selective dynamin-related GTPase Drp1 partial inhibitor (IC50=1.3 μM) over other dynamin family members, Opa 1 and dynamin-1 (IC50>100 μM)[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1.3 μM (Drp1)[1] |
| In Vitro | MB-0223 (30 μM; 48 hours) increases mitochondrial DNA levels in mfn1- knockout MEFs deficient in mitochondrial fusion[1]. MB-0223 (0-100 μM) is a partial inhibitor and exhibits a maximum inhibition of 67% of Drp1 activity. MB-0223 exhibits >100-fold selectivity for Drp1 over two other dynamin-like GTPases, Opa1 and Dnm1[1]. |
| References |
[1]. Ashley Mallat,et al. Characterization of Small Molecule Inhibitors of Drp1. |
| Molecular Formula | C26H27N5OS |
|---|---|
| Molecular Weight | 457.59 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: MB 0223
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: MB-0223
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: MB-0223
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
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