DCN1-UBC12-IN-1

Modify Date: 2024-01-06 18:46:52

DCN1-UBC12-IN-1 Structure
DCN1-UBC12-IN-1 structure
Common Name DCN1-UBC12-IN-1
CAS Number 2374827-31-1 Molecular Weight 521.61
Density N/A Boiling Point N/A
Molecular Formula C24H23N7O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DCN1-UBC12-IN-1


DCN1-UBC12-IN-1 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.86 nM. Anticardiac fibrotic effect[1].

 Names

Name DCN1-UBC12-IN-1

 DCN1-UBC12-IN-1 Biological Activity

Description DCN1-UBC12-IN-1 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.86 nM. Anticardiac fibrotic effect[1].
Related Catalog
In Vitro DCN1-UBC12-IN-1 (compound 44) possesses low cytotoxicity toward cardiac fibroblasts (CFs) with an IC50 of 9.97 μM for 24 h[1].
References

[1]. He ZX, et al. Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects. J Med Chem. 2022;65(1):163-190.

 Chemical & Physical Properties

Molecular Formula C24H23N7O3S2
Molecular Weight 521.61