DCN1-UBC12-IN-2

Modify Date: 2024-01-10 20:30:06

DCN1-UBC12-IN-2 Structure
DCN1-UBC12-IN-2 structure
 Common Name DCN1-UBC12-IN-2
CAS Number 2374827-47-9 Molecular Weight 542.03
Density N/A Boiling Point N/A
Molecular Formula C23H20ClN7O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DCN1-UBC12-IN-2


DCN1-UBC12-IN-2 is a potent and specific DCN1-UBC12 inhibitor (IC50=9.55 nM). DCN1-UBC12-IN-2 could specifically target DCN1-UBC12 interaction and relieve Ang II-induced cardiac fibroblast activation[1].

 Names

Name DCN1-UBC12-IN-2

 DCN1-UBC12-IN-2 Biological Activity

Description DCN1-UBC12-IN-2 is a potent and specific DCN1-UBC12 inhibitor (IC50=9.55 nM). DCN1-UBC12-IN-2 could specifically target DCN1-UBC12 interaction and relieve Ang II-induced cardiac fibroblast activation[1].
Related Catalog
In Vitro DCN1-UBC12-IN-2 (DN-2) possesses relatively low cytotoxicity toward cardiac fibroblasts (CFs) with an IC50 of 27.34 μM for 24 h.
References

[1]. He ZX, et al. Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects. J Med Chem. 2022;65(1):163-190.

 Chemical & Physical Properties

Molecular Formula C23H20ClN7O3S2
Molecular Weight 542.03
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Chemsrc provides DCN1-UBC12-IN-2(CAS#:2374827-47-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of DCN1-UBC12-IN-2 are included as well.>> amp version: DCN1-UBC12-IN-2

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