Thalidomide-NH-C6-NH2 hydrochloride
Modify Date: 2024-01-12 11:36:28
Thalidomide-NH-C6-NH2 hydrochloride structure
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Common Name | Thalidomide-NH-C6-NH2 hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 2375194-37-7 | Molecular Weight | 408.879 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H25ClN4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thalidomide-NH-C6-NH2 hydrochlorideThalidomide-NH-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
| Name | Pomalidomide-C6-NH2hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Thalidomide-NH-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C19H25ClN4O4 |
|---|---|
| Molecular Weight | 408.879 |
| Exact Mass | 408.156433 |
| Hazard Codes | Xi |
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| 1H-Isoindole-1,3(2H)-dione, 4-[(6-aminohexyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) |
| 4-[(6-Aminohexyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride (1:1) |