PDE4-IN-8

Modify Date: 2024-01-09 19:22:02

PDE4-IN-8 Structure
PDE4-IN-8 structure
Common Name PDE4-IN-8
CAS Number 2415085-45-7 Molecular Weight 327.18
Density N/A Boiling Point N/A
Molecular Formula C18H22BNO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PDE4-IN-8


PDE4-IN-8 (Example 5) is a potent PDE4 inhibitor with an IC50 of 0.93 nM for PDE4B2.PDE4-IN-8 has little effect on IL13 (IC50=4.04 nM), IL4 (IC50=36.33 nM), IFNy (IC50=2394 nM)[1].

 Names

Name PDE4-IN-8

 PDE4-IN-8 Biological Activity

Description PDE4-IN-8 (Example 5) is a potent PDE4 inhibitor with an IC50 of 0.93 nM for PDE4B2.PDE4-IN-8 has little effect on IL13 (IC50=4.04 nM), IL4 (IC50=36.33 nM), IFNy (IC50=2394 nM)[1].
Related Catalog
Target

PDE4B2:0.93 nM (IC50)

IL4:36.33 nM (IC50)

IL-13:4.04 nM (IC50)

References

[1]. Joseph Walter Strohbach, et al. Inhibiteurs de pde4 contenant du bore. WO2020070651A1.

 Chemical & Physical Properties

Molecular Formula C18H22BNO4
Molecular Weight 327.18
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: PDE4-IN-8
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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