MIF-IN-5

Modify Date: 2024-01-15 21:06:42

MIF-IN-5 Structure
MIF-IN-5 structure
Common Name MIF-IN-5
CAS Number 2582755-31-3 Molecular Weight 351.33
Density N/A Boiling Point N/A
Molecular Formula C18H14FN5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MIF-IN-5


MIF-IN-5 (compound 1d) is a potent and reversible macrophage migration inhibitory factor (MIF) competitive inhibitor with an IC50 of 4.8 μM and a Ki value of 3.3 μM, respectively[1].

 Names

Name MIF-IN-5

 MIF-IN-5 Biological Activity

Description MIF-IN-5 (compound 1d) is a potent and reversible macrophage migration inhibitory factor (MIF) competitive inhibitor with an IC50 of 4.8 μM and a Ki value of 3.3 μM, respectively[1].
Related Catalog
Target

IC50: 4.8 μM (MIF)[1] Ki: 3.3 μM (MIF)[1]

References

[1]. Xiao Z, Fokkens M, Chen D, et al. Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem. 2020;186:111849.

 Chemical & Physical Properties

Molecular Formula C18H14FN5O2
Molecular Weight 351.33