ITK/TRKA-IN-1
Modify Date: 2025-09-20 21:37:32
ITK/TRKA-IN-1 structure
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Common Name | ITK/TRKA-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 2655557-54-1 | Molecular Weight | 484.54 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H30F2N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ITK/TRKA-IN-1ITK/TRKA-IN-1 is a dual inhibitor of IL-2-inducible T-cell kinase (ITK) and tropomyosin receptor kinase A (TRKA) with an IC50 value of 1.0 nM and 96 % inhibition, respectively. |
| Name | ITK/TRKA-IN-1 |
|---|
| Description | ITK/TRKA-IN-1 is a dual inhibitor of IL-2-inducible T-cell kinase (ITK) and tropomyosin receptor kinase A (TRKA) with an IC50 value of 1.0 nM and 96 % inhibition, respectively. |
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| Related Catalog | |
| References |
[1]. Bagley SW, et al. Benzimidazole Derivatives. WO2021124155A1. |
| Molecular Formula | C25H30F2N6O2 |
|---|---|
| Molecular Weight | 484.54 |
| InChIKey | IDUVSAHDJQJJOH-BUYWVXTPSA-N |
| SMILES | Cc1cc2[nH]c(C3NNC4CC5(C)C(CC43)C5(F)F)nc2cc1N(C)C(=O)C(C)N1CCOCC1 |