PBRM1-BD2-IN-7
Modify Date: 2025-10-29 08:04:29
PBRM1-BD2-IN-7 structure
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Common Name | PBRM1-BD2-IN-7 | ||
|---|---|---|---|---|
| CAS Number | 2819989-68-7 | Molecular Weight | 286.76 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H15ClN2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PBRM1-BD2-IN-7PBRM1-BD2-IN-7 is a selective and cell-active polybromo-1 (PBRM1) bromodomain inhibitor. PBRM1-BD2-IN-7 has inhibitory activity for PBRM1-BD2 with an IC50 value of 0.29 μM. PBRM1-BD2-IN-7 can be used for the research of cancer[1]. |
| Name | PBRM1-BD2-IN-7 |
|---|
| Description | PBRM1-BD2-IN-7 is a selective and cell-active polybromo-1 (PBRM1) bromodomain inhibitor. PBRM1-BD2-IN-7 has inhibitory activity for PBRM1-BD2 with an IC50 value of 0.29 μM. PBRM1-BD2-IN-7 can be used for the research of cancer[1]. |
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| Related Catalog | |
| Target |
IC50: 0.29 μM (PBRM1-BD2)[1]. |
| In Vitro | PBRM1-BD2-IN-7 (0, 0.1, 1, and 10 μM; 5 days) selectively inhibit growth of a PBRM1-dependent prostate cancer cell line[1]. PBRM1-BD2-IN-7 has inhibitory activity for PBRM1-BD2 with IC50 value of 0.29 μM[1]. Cell Viability Assay[1] Cell Line: Human prostate cell lines LNCaP, PC3, and RWPE-1 Concentration: 0, 0.1, 1, and 10 μM Incubation Time: 5 days Result: Inhibited LNCaP growth at higher concentrations. |
| Molecular Formula | C16H15ClN2O |
|---|---|
| Molecular Weight | 286.76 |
| InChIKey | OKLYBCNMVQMCRF-UHFFFAOYSA-N |
| SMILES | Cc1cccc(C)c1C1NC(=O)c2c(Cl)cccc2N1 |