FGFR3-IN-4

Modify Date: 2024-01-06 00:03:38

FGFR3-IN-4 Structure
FGFR3-IN-4 structure
Common Name FGFR3-IN-4
CAS Number 2833706-13-9 Molecular Weight 485.97
Density N/A Boiling Point N/A
Molecular Formula C26H24ClN7O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FGFR3-IN-4


FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].

 Names

Name FGFR3-IN-4

 FGFR3-IN-4 Biological Activity

Description FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].
Related Catalog
Target

FGFR3:< 50 nM (IC50)

In Vitro FGFR3 (example 297) 抑制 FGFR3 活性,IC50 值小于 50 nM[1]。
References

[1]. Abraham, et al. Preparation of substituted pyrazolo[1,5-a]pyridine-3-carbonitriles and imidazo[1,2-a]pyridine-3-carbonitriles as FGFR3 inhibitors. WO2022187443.

 Chemical & Physical Properties

Molecular Formula C26H24ClN7O
Molecular Weight 485.97
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