FGFR3-IN-4

Modify Date: 2024-01-06 00:03:38

FGFR3-IN-4 structure	Common Name	FGFR3-IN-4
	CAS Number	2833706-13-9	Molecular Weight	485.97
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₄ClN₇O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FGFR3-IN-4

FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].

Name	FGFR3-IN-4

Description	FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR
Target	FGFR3:< 50 nM (IC50)
In Vitro	FGFR3 (example 297) 抑制 FGFR3 活性，IC50 值小于 50 nM[1]。
References	[1]. Abraham, et al. Preparation of substituted pyrazolo[1,5-a]pyridine-3-carbonitriles and imidazo[1,2-a]pyridine-3-carbonitriles as FGFR3 inhibitors. WO2022187443.

Molecular Formula	C₂₆H₂₄ClN₇O
Molecular Weight	485.97