FGFR3-IN-4

Modify Date: 2025-10-27 14:11:40

FGFR3-IN-4 Structure
FGFR3-IN-4 structure
 Common Name FGFR3-IN-4
CAS Number 2833706-13-9 Molecular Weight 485.97
Density N/A Boiling Point N/A
Molecular Formula C26H24ClN7O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FGFR3-IN-4


FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].

 Names

Name FGFR3-IN-4

 FGFR3-IN-4 Biological Activity

Description FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].
Related Catalog
Target

FGFR3:< 50 nM (IC50)

In Vitro FGFR3 (example 297) 抑制 FGFR3 活性，IC50 值小于 50 nM[1]。
References

[1]. Abraham, et al. Preparation of substituted pyrazolo[1,5-a]pyridine-3-carbonitriles and imidazo[1,2-a]pyridine-3-carbonitriles as FGFR3 inhibitors. WO2022187443.

 Chemical & Physical Properties

Molecular Formula C26H24ClN7O
Molecular Weight 485.97
InChIKey KBCMVZNCBWKZQE-GOSISDBHSA-N
SMILES Cc1c(-c2cc(OC(C)c3ccccc3C#N)c3c(Cl)cnn3c2)cnn1C1CCN(C#N)CC1
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Chemsrc provides FGFR3-IN-4(CAS#:2833706-13-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of FGFR3-IN-4 are included as well.>> amp version: FGFR3-IN-4

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