FGFR3-IN-1

Modify Date: 2025-08-27 16:34:14

FGFR3-IN-1 structure	Common Name	FGFR3-IN-1
	CAS Number	2428743-04-6	Molecular Weight	581.73
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₉N₉O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FGFR3-IN-1

FGFR3-IN-1 (compound 1) is a fibroblast growth factor receptor (FGFR) inhibitor, with IC50s of 40 nM, 5.1 nM, and 12 nM for FGFR1, 2, and 3, respectively. FGFR3-IN-1 can be used for the research of bladder cancer[1].

Name	FGFR3-IN-1

Description	FGFR3-IN-1 (compound 1) is a fibroblast growth factor receptor (FGFR) inhibitor, with IC50s of 40 nM, 5.1 nM, and 12 nM for FGFR1, 2, and 3, respectively. FGFR3-IN-1 can be used for the research of bladder cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR
Target	FGFR1:40 nM (IC50) FGFR2:5.1 nM (IC50) FGFR3:12 nM (IC50)
References	[1]. Kuriwaki I, et, al. Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2. Bioorg Med Chem. 2020 May 15;28(10):115453.

Molecular Formula	C₂₈H₃₉N₉O₃S
Molecular Weight	581.73

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