2,6-Dihydroxybenzoic acid

Modify Date: 2024-01-02 23:30:50

2,6-Dihydroxybenzoic acid Structure
2,6-Dihydroxybenzoic acid structure
Common Name 2,6-Dihydroxybenzoic acid
CAS Number 303-07-1 Molecular Weight 154.120
Density 1.6±0.1 g/cm3 Boiling Point 343.7±32.0 °C at 760 mmHg
Molecular Formula C7H6O4 Melting Point 165 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 175.8±21.6 °C

 Use of 2,6-Dihydroxybenzoic acid


2,6-Dihydroxybenzoic acid is a secondary metabolite of salicylic acid which has been hydrolyzed by liver enzymes during phase I metabolism.

 Names

Name 2,6-dihydroxybenzoic acid
Synonym More Synonyms

 2,6-Dihydroxybenzoic acid Biological Activity

Description 2,6-Dihydroxybenzoic acid is a secondary metabolite of salicylic acid which has been hydrolyzed by liver enzymes during phase I metabolism.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Cokgor EU, et al. Biodegradation kinetics of peptone and 2,6-dihydroxybenzoic acid by acclimated dual microbial culture. Bioresour Technol. 2011 Jan;102(2):567-75.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 343.7±32.0 °C at 760 mmHg
Melting Point 165 °C (dec.)(lit.)
Molecular Formula C7H6O4
Molecular Weight 154.120
Flash Point 175.8±21.6 °C
Exact Mass 154.026611
PSA 77.76000
LogP 2.24
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.671

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG8578000
CHEMICAL NAME :
Benzoic acid, 2,6-dihydroxy-
CAS REGISTRY NUMBER :
303-07-1
BEILSTEIN REFERENCE NO. :
2209755
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H6-O4
MOLECULAR WEIGHT :
154.13

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 196,478,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 89,1392,1969

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DG8578000
HS Code 29182990

 Synthetic Route

 Customs

HS Code 2918290000
Summary HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

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 Synonyms

EINECS 206-134-8
Gamma-Resorcylic Acid
2-Carboxyresorcinol
γ-Resorcylic acid
Benzoic acid,2,6-dihydroxy
2,6-dihydroxy-benzoic acid
2,5-DIFLUOROBENZYLSULFONAMIDE
2,6-Dihydroxybenzoic acid
g-Resorcylic Acid
2,6-Resorcylic acid
6-Hydroxysalicylic acid
MFCD00002462
Benzoic acid, 2,6-dihydroxy-
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